%0 Journal Article
%@ 0866-8612
%A Dang, Thanh Hai
%A Nguyen, Dai Thanh
%A Pham, Thi Minh Trang
%A Dang, Cao Cuong
%A Hoang, Kim Phuc
%A Pham, Bao Son
%A Le, Sy Vinh
%A Le, Si Quang
%A Phan, Thi Thu Hang
%A Do, Duc Dong
%D 2014
%F SisLab:2086
%I VNU Journal of Science
%J VNU Journal of Computer Science and Communication Engineering
%N 3
%P 31-35
%T Preliminary results on the whole genome analysis of a Vietnamese individual
%U https://eprints.uet.vnu.edu.vn/eprints/id/eprint/2086/
%V 30
%X We present some preliminary results on the whole genome analysis of an anonymous Kinh Vietnamese (KHV) individual that was deeply sequenced to 34-fold using the Illumina sequencing technology. The sequenced genome covered 99.85% of the human reference genome (GRCh37). We discovered (1) 3408825 single polymorphism nucleotides (SNPs) of which 41396 (1.2%) were novel, (2) 654024 short indels of which 35263 (5.4%) were novel, i.e. not present in the dbSNP and 1000 genomes project databases. We also detected 10611 large SVs (the length  ≥ 100bp) of  four types, i.e. large indels (90.6%), the inter-chromosomal translocations (3.1%), the inversions (3.4%) and the intra-chromosomal translocations (2.9%). This study is our initial step toward large-scale projects on Vietnamese population.