eprintid: 2212
rev_number: 9
eprint_status: archive
userid: 280
dir: disk0/00/00/22/12
datestamp: 2016-12-31 10:18:46
lastmod: 2016-12-31 10:18:46
status_changed: 2016-12-31 10:18:46
type: conference_item
metadata_visibility: show
creators_name: Le, Thi Hien
creators_name: Le, Khac Quynh
creators_name: Vu, Thi Huyen
creators_name: Nguyen, Thi Yen
creators_name: Bui, Dinh Tu
creators_name: Pham, Hong Nhung
creators_name: Do, Thi Huong Giang
creators_name: Nguyen, Huu Duc
creators_id: lehien@vnu.edu.vn
creators_id: buidinhtu@vnu.edu.vn
creators_id: giangdth@vnu.edu.vn
creators_id: ducnh@vnu.edu.vn
title: Detection of magnetically labeled DNA by a magnetic sensor 
operating with a disposable card
ispublished: pub
subjects: Phys
divisions: fac_physic
abstract: Disposable cards with immobilized bioreceptors  are being increasingly investigated and developed in biomedical analysis systems because they have significant advantages. In our work, a biosensor system consisting of an anisotropic magnetoresistive (AMR) sensor operating with a disposable card was developed for magnetically labeled DNA detection. The SPA/SAA/APTES/PDMS/Si as-prepared disposable card involves DNA probes specific for the 16S rRNA gene of Streptococcus suis. A single-stranded target DNA was hybridized with the DNA probe on the disposable card, which was subsequently magnetically labeled with superparamagnetic beads for detection using the AMR sensor. An almost linear response between the output signal of the AMR sensor and amount of single-stranded target DNA varied from 4.5 to 18 pmol was identified. This novel approach opens up new possibilities for the development of a sensitive, easy to use and low-cost DNA biosensor system.
date: 2016-11-04
date_type: published
official_url: http://nec-hus.edu.vn/iwamn2016/
full_text_status: none
pres_type: speech
pagerange: 108
event_title: International Workshop on Advanced Materials and Nanotechnology 2016 (IWAMN 2016)
event_location: Hanoi, Vietnam
event_dates: 3-5 November 2016
event_type: workshop
refereed: TRUE
citation:   Le, Thi Hien and Le, Khac Quynh and Vu, Thi Huyen and Nguyen, Thi Yen and Bui, Dinh Tu and Pham, Hong Nhung and Do, Thi Huong Giang and Nguyen, Huu Duc  (2016) Detection of magnetically labeled DNA by a magnetic sensor operating with a disposable card.  In: International Workshop on Advanced Materials and Nanotechnology 2016 (IWAMN 2016), 3-5 November 2016, Hanoi, Vietnam.