eprintid: 2319 rev_number: 10 eprint_status: archive userid: 270 dir: disk0/00/00/23/19 datestamp: 2016-12-29 02:48:51 lastmod: 2016-12-29 02:48:51 status_changed: 2016-12-29 02:48:51 type: conference_item metadata_visibility: show creators_name: Robbins, Hannah creators_name: Liu, Changqing creators_name: Hu, Sijung creators_name: Bui, Thanh Tung creators_name: Aoyagi, Masahiro creators_id: h.r.robbins@outlook.com creators_id: c.liu@lboro.ac.uk creators_id: s.hu@lboro.ac.uk creators_id: tungbt@vnu.edu.vn creators_id: m-aoyagi@aist.go.jp title: Integration of a microfluidic chip with multiplexed optical fluorescence detector through anisotropic etching of Si using Tetramethylammonium hydroxide (TMAH) ispublished: pub subjects: ECE divisions: fac_fet keywords: Etching, Fluorescence, Lighting, microfluidics, Optical device fabrication, silicon abstract: Point of care testing (POCT) systems, are widely used to firstly, diagnose and secondly, monitor a number of illnesses and infectious diseases. This research aims to develop the integration between an optical fluorescence system and a microfluidic chip - through the use of advanced manufacturing techniques, such as anisotropic wet etching of Silicon (Si) wafers. The fabricated Si microfluidic chips may integrate into an existing POCT system and provide a potential avenue into multiplexed detection. Zemax and OptiCAD simulation packages were used to confirm the validity of the integrated microfluidic chip design. A testable microfluidic chip, using anisotropic wet etching of a Si wafer by Tetramethylammonium hydroxide (TMAH) etching solution, was fabricated. The process used a mask-less photoresist design, allowing for an easier and cost effective developmental stage in order to provide a proof of concept design. Currently, the TMAH etching process provides the required 370µm etch depth, to house a micro-capillary. date: 2016-09 full_text_status: none pres_type: lecture pagerange: 1-6 event_title: 2016 6th Electronic System-Integration Technology Conference (ESTC) event_type: conference refereed: TRUE citation: Robbins, Hannah and Liu, Changqing and Hu, Sijung and Bui, Thanh Tung and Aoyagi, Masahiro (2016) Integration of a microfluidic chip with multiplexed optical fluorescence detector through anisotropic etching of Si using Tetramethylammonium hydroxide (TMAH). In: 2016 6th Electronic System-Integration Technology Conference (ESTC).