eprintid: 2380
rev_number: 11
eprint_status: archive
userid: 312
dir: disk0/00/00/23/80
datestamp: 2016-12-31 10:22:45
lastmod: 2016-12-31 10:22:45
status_changed: 2016-12-31 10:22:45
type: article
metadata_visibility: show
creators_name: Pham, Thi Bich Dao
creators_name: Nguyen, Dinh Tuan
creators_name: Tran, Dang Khoa
creators_name: Chu, Thi Huyen
creators_name: Do, Hoang Thanh
creators_name: Nguyen, Thi Hoai Ha
creators_id: khoatd@vnu.edu.vn
title: Lipid biosynthesis of ten Thraustochyrid strains isolated from mangrove Xuan Thuy, Nam Dinh
ispublished: pub
subjects: Phys
divisions: fac_physic
abstract: The features of polyunsaturated fatty acid-PUFA structures were corresponded to each separate functions  as adjusting the cellular physiology and gene expression. Therefore, lack of PUFA could lead to abnormalities in skin, kidney, neural networks, immune responses and inflammation; cardiovascular, endocrine, respiratory and reproductive systems. In fish oil, PUFA content were low, thus it was difficult to produce on a large scale. Therefore, the exploration of PUFA sources particularly as arachidonic acid-AA, eicosapentaenoic acid EPA, docosapentaenoic acid-DPA/DHA attracted many researches. Heterotrophic microalgae Thraustochytrids were capable of producing high amounts of DHA and PUFA composition varied. DHA can be synthesized by the metabolism of AA, EPA and DPA. The different types of PUFA reflected relationships in classification. Ten heterotrophic microalgae thraustochytrids isolated from mangrove Xuan Thuy, Nam Dinh contain fatty acid composition varied from C12 to C28. Especially, they had two important fatty acids of PUFA as EPA and DPA. Polyunsaturated fatty acids - PUFA content of ten thraustochytrid strains were from 28.95 to 49.62% total lipid. DPA compared to other PUFA were high for all thraustochytrid strains studied, accounting 20.22 to 39.35% TFA. Ten thraustochytrid strains had the highest growth with carbon source as glucose, total lipid reached 7 to 12.35 % dry weight biomass after 72 hours. Growth rate and lipid biosynthesis in organic nitrogen source were higher than in inorganic nitrogen sources. The best source of nitrogen for growth and lipid biosynthesis of ten thraustochytrid strains is yeast extract, total lipid were 8.57 to 18.87% dry weight biomass after 72 hours.
date: 2016
date_type: published
full_text_status: public
publication: Journal of Biotechnology
volume: 14
number: 2
pagerange: 1-8
refereed: FALSE
issn: ISSN: 1811-4989
citation:   Pham, Thi Bich Dao and Nguyen, Dinh Tuan and Tran, Dang Khoa and Chu, Thi Huyen and Do, Hoang Thanh and Nguyen, Thi Hoai Ha  (2016) Lipid biosynthesis of ten Thraustochyrid strains isolated from mangrove Xuan Thuy, Nam Dinh.  Journal of Biotechnology, 14  (2).   pp. 1-8.  ISSN ISSN: 1811-4989     
document_url: https://eprints.uet.vnu.edu.vn/eprints/id/eprint/2380/1/LIPID%20BIOSYNTHESIS%20.pdf