TY  - CONF
ID  - SisLab2680
UR  - http://www.aseanpharmnet2017.net/
A1  - Le, Thi Hien
A1  - Nguyen, Thi Yen
A1  - Tuong, Van Thuan
A1  - Tran, Thi Hai Yen
A1  - Vu, Thi Huyen
Y1  - 2017/11//
N2  - Niosome encapsulated curcumin were prepared by ethanol injection method with continuous ethanol evaporation using non-ionic surfactant span 80, cholesterol and curcumin. Curcumin-niosomes were purified from unencapsulated curcumin and impurities by size exclusion chromatography. Field emission scanning electron microscopy (FE-SEM) demonstrated that curcumin-niosomes had relatively uniform, spherical shapes with estimated diameters of 50 nm. Dynamic light scattering (DLS) analysis indicated that the size of particles hardly depended on the solvent evaporation time. Niosomal encapsulation efficiency of curcumin (EE), which was determined by fluorospectrometer, incredibly increased after 2-hour ethanol evaporation. It reached the highest value of 98% after 5 hours of ethanol evaporation for the mixture of span80, cholesterol, curcumin in a molar ratio of 45: 30: 1.
TI  - Preparation and characterization of niosome encapsulated curcumin
SP  - 208
M2  - Kuala Lumpur
AV  - public
EP  - 214
T2  - The 2nd International Conference On Pharmacy Education and Research Network of ASEAN
ER  -