@inproceedings{SisLab2742, booktitle = {The 6th International Workshop on Nanotechnology and Application (IWNA)}, month = {November}, title = {Circular electrodes stepping manipulation platform for A549 cancer cell detection}, author = {Quang Loc Do and Thu Trang Nguyen and Thanh Tung Bui and Thi Thuy Ha Tran and Van Chieu Le and Thi Thuong Lan Vo and Thi My Nhung Hoang and Chun-Ping Jen and Duc Trinh Chu}, year = {2017}, pages = {649--652}, url = {https://eprints.uet.vnu.edu.vn/eprints/id/eprint/2742/}, abstract = {In this paper, a novel design of an impedance sensor integrated on stepping dielectrophoresis manipulation platform for biological cells detection is presented. The platform consists of fluidic working chamber and manipulating/sensing gold electrodes. Gold electrodes are patterned on glass substrate and protected by an insulating layer to avoid the direct contact between metal electrodes and electrolyte. The outer circular electrodes implement hiological cell manipulating function while the inner electrodes construct sensing electrodes pair which are connected to an impedance analyzer to detect the appearanceo of biological cells on the sensing area. Several experiments have been implemented to investigate the performance of trapping A549 cell line based on aptamer immobilization on gold surface, and impedance spectroscopy readout method.} }