%0 Conference Paper
%A Do, Quang Loc
%A Nguyen, Thu Trang
%A Bui, Thanh Tung
%A Tran, Thi Thuy Ha
%A Le, Van Chieu
%A Vo, Thi Thuong Lan
%A Hoang, Thi My Nhung
%A Jen, Chun-Ping
%A Chu, Duc Trinh
%B The 6th International Workshop on Nanotechnology and Application (IWNA)
%C Phan Thiet, Vietnam
%D 2017
%F SisLab:2742
%P 649-652
%T Circular electrodes stepping manipulation platform for A549 cancer cell detection
%U https://eprints.uet.vnu.edu.vn/eprints/id/eprint/2742/
%X In this paper, a novel design of an impedance sensor integrated on stepping dielectrophoresis manipulation platform for biological cells detection is presented. The platform consists of fluidic working chamber and manipulating/sensing gold electrodes. Gold electrodes are patterned on glass substrate and protected by an insulating layer to avoid the direct contact between metal electrodes and electrolyte. The outer circular electrodes implement hiological cell manipulating function while the inner electrodes construct sensing electrodes pair which are connected to an impedance analyzer to detect the appearanceo of biological cells on the sensing area. Several experiments have been implemented to investigate the performance of trapping A549 cell line based on aptamer immobilization on gold surface, and impedance spectroscopy readout method.