eprintid: 2958
rev_number: 8
eprint_status: archive
userid: 15
dir: disk0/00/00/29/58
datestamp: 2018-06-07 07:01:43
lastmod: 2018-06-07 07:01:43
status_changed: 2018-06-07 07:01:43
type: article
metadata_visibility: show
creators_name: Dang, Cao Cuong
creators_name: Peón, Antonio
creators_name: Ballester, Pedro
creators_id: cuongdc@vnu.edu.vn
title: Unearthing new genomic markers of drug response by improved measurement of discriminative power
ispublished: pub
subjects: IT
subjects: isi
divisions: fac_fit
abstract: Oncology drugs are only effective in a small proportion of cancer patients. Our current ability to identify these responsive patients before treatment is still poor in most cases. Thus, there is a pressing need to discover response markers for marketed and research oncology drugs. Screening these drugs against a large panel of cancer cell lines has led to the discovery of new genomic markers of in vitro drug response. However, while the identification of such markers among thousands of candidate drug-gene associations in the data is error-prone, an appraisal of the effectiveness of such detection task is currently lacking.
date: 2018-02
date_type: published
official_url: https://doi.org/10.1186/s12920-018-0336-z
full_text_status: public
publication: BMC Medical Genomics
volume: 11
number: 1
pagerange: 10
refereed: TRUE
citation:   Dang, Cao Cuong and Peón, Antonio and Ballester, Pedro  (2018) Unearthing new genomic markers of drug response by improved measurement of discriminative power.  BMC Medical Genomics, 11  (1).   p. 10.      
document_url: https://eprints.uet.vnu.edu.vn/eprints/id/eprint/2958/1/untitled.pdf