eprintid: 3437 rev_number: 9 eprint_status: archive userid: 282 dir: disk0/00/00/34/37 datestamp: 2019-06-03 04:14:06 lastmod: 2019-06-03 04:14:06 status_changed: 2019-06-03 04:14:06 type: article metadata_visibility: show creators_name: Hoang, Thi Diep creators_name: Chernomor, Olga creators_name: Arndt, von Haeseler creators_name: Bui, Quang Minh creators_name: Le, Sy Vinh creators_id: diepht@vnu.edu.vn creators_id: vinhls@vnu.edu.vn title: UFBoot2: Improving the Ultrafast Bootstrap Approximation ispublished: pub subjects: IT subjects: Scopus subjects: isi divisions: fac_fit abstract: Abstract The standard bootstrap (SBS), despite being computationally intensive, is widely used in maximum likelihood phylogenetic analyses. We recently proposed the ultrafast bootstrap approximation (UFBoot) to reduce computing time while achieving more unbiased branch supports than SBS under mild model violations. UFBoot has been steadily adopted as an efficient alternative to SBS and other bootstrap approaches. Here, we present UFBoot2, which substantially accelerates UFBoot and reduces the risk of overestimating branch supports due to polytomies or severe model violations. Additionally, UFBoot2 provides suitable bootstrap resampling strategies for phylogenomic data. UFBoot2 is 778 times (median) faster than SBS and 8.4 times (median) faster than RAxML rapid bootstrap on tested data sets. UFBoot2 is implemented in the IQ-TREE software package version 1.6 and freely available at http://www.iqtree.org. date: 2018-02-01 date_type: published publisher: Oxford University Press official_url: https://dx.doi.org/10.1093/molbev/msx281 id_number: 10.1093/molbev/msx281 full_text_status: public publication: Molecular Biology and Evolution volume: 35 number: 2 pagerange: 518-522 refereed: TRUE issn: 0737-4038 related_url_url: https://academic.oup.com/mbe related_url_type: pub citation: Hoang, Thi Diep and Chernomor, Olga and Arndt, von Haeseler and Bui, Quang Minh and Le, Sy Vinh (2018) UFBoot2: Improving the Ultrafast Bootstrap Approximation. Molecular Biology and Evolution, 35 (2). pp. 518-522. ISSN 0737-4038 document_url: https://eprints.uet.vnu.edu.vn/eprints/id/eprint/3437/1/MinhChung_CongTrinh1.pdf