TY - JOUR ID - SisLab3934 UR - https://eprints.uet.vnu.edu.vn/eprints/id/eprint/3934/ IS - 5 A1 - Parlavantzas, Nikos A1 - Pham, Manh Linh A1 - Morin, Christine A1 - Arnoux, Sandie A1 - Beaunée, Gaël A1 - Qi, Luyuan A1 - Gontier, Philippe A1 - Ezanno, Pauline N2 - The cloud has emerged as an attractive platform for resource-intensive scientific applications, such as epidemic simulators. However, building and executing such applications in the cloud presents multiple challenges, including exploiting elasticity, handling failures, and simplifying multi-cloud deployment. To address these challenges, this paper proposes a novel service-based framework called DiFFuSE that enables simulation applications with a bag-of-tasks structure to fully exploit cloud platforms. This paper describes how the framework is applied to restructure two legacy applications, simulating the spread of bovine viral diarrhea virus and Mycobacterium avium subspecies paratuberculosis, into elastic cloud-native applications. Experimental results show that the framework enhances application performance and allows exploring different cost-performance trade-offs while supporting automatic failure handling and elastic resource acquisition from multiple clouds. VL - 32 TI - A Service-based Framework for Building and Executing Epidemic Simulation Applications in the Cloud AV - public EP - 16 Y1 - 2020/03/10/ PB - John Wiley & Sons Inc JF - Concurrency and Computation: Practice and Experience KW - Cloud computing; Epidemic simulation; High Performance Computing; Simulation models SN - 1532-0626 SP - 1 ER -