eprintid: 4540 rev_number: 6 eprint_status: archive userid: 270 dir: disk0/00/00/45/40 datestamp: 2021-06-28 16:41:01 lastmod: 2021-06-28 16:41:01 status_changed: 2021-06-28 16:41:01 type: article metadata_visibility: show creators_name: Vu, Quoc Tuan creators_name: Nguyen, Ngoc Viet creators_name: Hoang, Bao Anh creators_name: Jen, Chun-Ping creators_name: Chu, Duc Trinh creators_name: Bui, Thanh Tung creators_id: vqtuan0211@gmail.com creators_id: vietnn.mt@gmail.com creators_id: anhbh@vnu.edu.vn creators_id: Chun-Ping@gmail.com creators_id: trinhcd@vnu.edu.vn creators_id: tungbt@vnu.edu.vn title: Development of a Compact Electrical Impedance Measurement Circuit for Protein Detection Two-electrode Impedance Micro-sensor ispublished: pub subjects: ElectronicsandComputerEngineering subjects: isi divisions: cetr_uet divisions: fac_fet abstract: Development of compact and low-cost electronic circuits in the biosensor field is an essential demand. Especially, the design of noise reduction sections plays an important role in the measurement of small biosensing signals. This study develops an electrical impedance measurement circuit board to apply in the protein pre-concentration and detection microfluidic chips with integrated two-electrode impedance micro-sensor. A lock-in amplifier is applied in the circuit board to measure the impedance profile in the frequency range 10–200 kHz. An investigation on several ratios of signal to noise (SNRs) is conducted to indicate the ability of the proposed design in eliminating noise signals. Subsequently, a total impedance and series capacitance-based analysis approach from the recorded impedance data is demonstrated to be suitable for this protein chip in the frequencies range from 10 to 200 kHz. The obtained results enable a potential method in point-of-care diagnostic applications. date: 2021-03-14 date_type: published publisher: Taylor and Prancis official_url: http://dx.doi.org/10.1080/03772063.2021.1893230 id_number: 10.1080/03772063.2021.1893230 full_text_status: none publication: IETE Journal of Research pagerange: 1-9 refereed: TRUE issn: 0377-2063 related_url_url: https://www.tandfonline.com/doi/abs/10.1080/03772063.2021.1893230 related_url_type: pub funders: Vietnamese Ministry of Science and Technology projects: NDT.101.TW/21 citation: Vu, Quoc Tuan and Nguyen, Ngoc Viet and Hoang, Bao Anh and Jen, Chun-Ping and Chu, Duc Trinh and Bui, Thanh Tung (2021) Development of a Compact Electrical Impedance Measurement Circuit for Protein Detection Two-electrode Impedance Micro-sensor. IETE Journal of Research . pp. 1-9. ISSN 0377-2063