%A Thi Thu Huong Bui
%A Thi Hong Nguyen
%A Duc Ha Chu
%A Thi Quyen Ha
%A Phuong Thu Pham
%A Thi Thu Huong Phung
%A Thi Ngoc Quynh Le
%A Quoc Trung Nguyen
%A Huy Gioi Dong
%A Thanh Hai Nguyen
%A Thi Thao Ninh
%J Tạp chí Khoa học Nông nghiệp Việt Nam
%T Recent Advances and Future Perspectives for the Improvement 
of Stress Tolerance in Rice Breeding Using CRISPR/Cas9
%X Rice (Oryza sativa L.) is one of the most important staple crops that is widely cultivated in the world. Due to the 
critical role of rice in the global food security, great efforts have been made in order to develop new rice varieties with 
good agronomic traits, such as biotic and abiotic stress tolerance. The CRISPR/Cas9 has emerged as a promising 
system for the improvement of various traits of crop plants because of its efficiency, simplicity, and versatility. In this 
mini review, we discussed the applications of the CRISPR/Cas9 gene editing system to improve a wide range of traits 
in rice varieties adapted to unfavorable conditions. Specifically, a number of functional and regulatory genes that are 
associated with diseases (rice blast, bacterial blight) and pesticide resistance and abiotic stress (salinity, drought, and 
cold) tolerance have been functionally characterized via the mutants produced by the CRISPR/Cas9 system. 
Additionally, the advances and limitations of using CRISPR/Cas9 system in rice plants were discussed. Taken 
together, our paper could provide a solid foundation for further application of genome editing tools in plant breeding 
for tackling climate change.
%D 2022
%P 123-132
%L SisLab4707