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An Efficient Ant Colony Optimization Algorithm for Protein Structure Prediction

Do, Duc Dong and Thai Dinh, Phuc and Vu, Thi Ngoc Anh and Nguyen, Linh Trung (2018) An Efficient Ant Colony Optimization Algorithm for Protein Structure Prediction. In: 12th International Symposium on Medical Information and Communication Technology (ISMICT), March 26-28, Sydney, Australia.

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Protein structure prediction is considered as one of the most long-standing and challenging problem in bioinformatics. In this paper, we present an efficient ant colony optimization algorithm to predict the protein structure on three-dimensional face-centered cubic lattice coordinates, using the hydrophobic–polar model and the Miyazawa-Jernigan model to calculate the free energy. The reinforcement learning information is expressed in the k-order Markov model, and the heuristic information is determined based on the increase of the total energy. On a set of benchmark proteins, the results show a remarkable efficiency of our algorithm in comparison with several state-of-the-art algorithms.

Item Type: Conference or Workshop Item (Paper)
Subjects: Electronics and Communications
Information Technology (IT)
Divisions: Advanced Insitute of Engineering and Technology (AVITECH)
Faculty of Electronics and Telecommunications (FET)
Faculty of Information Technology (FIT)
Depositing User: A/Prof. Linh Trung Nguyen
Date Deposited: 18 Apr 2018 08:49
Last Modified: 18 Apr 2018 08:49

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