Do, Duc Dong and Thai Dinh, Phuc and Vu, Thi Ngoc Anh and Nguyen, Linh Trung (2018) An Efficient Ant Colony Optimization Algorithm for Protein Structure Prediction. In: 12th International Symposium on Medical Information and Communication Technology (ISMICT), March 26-28, Sydney, Australia.
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Abstract
Protein structure prediction is considered as one of the most long-standing and challenging problem in bioinformatics. In this paper, we present an efficient ant colony optimization algorithm to predict the protein structure on three-dimensional face-centered cubic lattice coordinates, using the hydrophobic–polar model and the Miyazawa-Jernigan model to calculate the free energy. The reinforcement learning information is expressed in the k-order Markov model, and the heuristic information is determined based on the increase of the total energy. On a set of benchmark proteins, the results show a remarkable efficiency of our algorithm in comparison with several state-of-the-art algorithms.
| Item Type: | Conference or Workshop Item (Paper) |
|---|---|
| Subjects: | Electronics and Communications Information Technology (IT) |
| Divisions: | Advanced Insitute of Engineering and Technology (AVITECH) Faculty of Electronics and Telecommunications (FET) Faculty of Information Technology (FIT) |
| Depositing User: | A/Prof. Linh Trung Nguyen |
| Date Deposited: | 18 Apr 2018 08:49 |
| Last Modified: | 18 Apr 2018 08:49 |
| URI: | http://eprints.uet.vnu.edu.vn/eprints/id/eprint/2948 |
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